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Increase the NaCl concentration (up to 2 M) in the purification buffers to reduce the binding of contaminants as a result of nonspecific ionic interactions

Cancer Res 2008, 68 (22), 92809290

2A and 2C, analytical solutions (discussed in the Methods section) of the linearized EGFR and GPCR models (dotted lines) provide reasonable approximations to the numerical solutions (solid lines)