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Nevertheless, metabolic disorders of brain cells usually involve the dysfunction of various pathways or networks rather than the alteration of individual metabolites 48,49

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278 The Pseudomonas-rich microbiome may suppress the virulence of potential pathogens and promote the restoration of the lung microbiome to a healthy state

In the early phase of repair, transient ROS bursts from infiltrating neutrophils and macrophages facilitate the clearance of damaged matrix and apoptotic cells, acting as upstream activators of cytokine release and immune resolution