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For people who do need injected vitamin B12, it may be possible to consider self-injection to reduce the workload for primary care teams. He also explained that when it comes to people with low/borderline readings in association with no or vague symptoms, many GPs will err on the side of caution and recommend vitamin B12 treatment because the risks from under-treatment will be much higher than from over-treatment

Its used more when cells are growing, making new fats or membranes (fatty acid synthesis), or dealing with higher levels of oxidative stress

James MO, Jahn SC, Zhong G, Smeltz MG, Hu Z, Stacpoole PW

This is an oversimplification of how one-carbon metabolism works