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Beyond antioxidant defense, it boosts white blood cell activity to strengthen immune function, helps build collagen in skin, joints, bones, and blood vessels, and speeds tissue repair and wound healing
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It also impairs base and nucleotide excision repair pathways and causes widespread epigenetic dysregulation, such as aberrant DNA methylation and histone modification, that silence tumor suppressor genes [176]
Moreover, replacing 10% intakes of dietary VB6, VC, VE, and folate-equivalent in the morning with that in the evening reduced CVD mortality by 4, 4, 4, and 5% when their total daily dietary intakes were held constant
