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In further, the unchanged APX but higher SOD and CAT activities suggest that H 2 O 2 was produced at chloroplast but accumulated in the cytoplasm
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Considering that only a limited volume of aspirate can be withdrawn, this means that there will typically be an intensive culturing process to expand the MSCs, especially if the cells are to be used allogenically 76,79
The accumulated reactive oxygen species (ROS) and reactive nitrogen species (RNS), in turn, cause damage to cells and tissues and may lead to inflammation
