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Description
and (iv) promotion of mitochondrial dysfunction, compromising ATP generation essential for contraction and relaxation (3739)
The CSNB mutant T94 2.61 I mutant is constitutively active 18,19 but does not show increased dark-state activity compared to the WT 16 , despite it results in extremely long-lived Meta II intermediate 14,18 E134 3.49 Q exhibits 1.5-fold dark-state activity relative to WT and is constitutively active 8,15
Glutathione is a powerful antioxidant that supports detoxification and combats oxidative stress
2 , a007039 (2012)
