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Description
A40 reduces P-glycoprotein at the bloodbrain barrier through the ubiquitinproteasome pathway
Stable complex concentrations after peptide exchange were measured using the Flex-T HLA Class I ELISA assay (BioLegend) according to the manufacturers instructions (BioLegend, 280301, 421701, 280302, 280303, 423501)
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It is a synthetic compound derived by modifying the structure of -tocopherol, replacing its hydrophobic polyisoprenoid tail with a hydrophilic carboxyl group
