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10.1021/jm701490g 78 LukaszukA.DemaegdtH.Van Den EyndeI.VanderheydenP.VauquelinG.TourwD
Crosses the Blood-Brain Barrier Unlike many peptides and growth factors, Dihexa is orally bioavailable and crosses the BBB , meaning it can be taken as an oral tablet and still reach brain tissues in therapeutic concentrations
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Cell lines and reagents The immortalized non-tumorigenic normal ovarian epithelial T72 cell line and the tumorigenic HRAS G12V -transformed T72Ras cell line were generated as previously described 12,32
