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5 Antioxidants The therapeutic approaches currently being explored in FRDA are focused on either increase the levels of frataxin or mitigating the out-turn of frataxin loss

Modulation of rat erythrocyte antioxidant defense system by buthionine sulfoximine and its reversal by glutathione monoester therapy. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease, 1688(2), 121-129

The signaling processes responsive to glucose activation of GLUT2 include the activation of the transcription factor ChREBP

In preclinical research, AOD has been associated with increased lipolysis (fat breakdown) and reduced lipogenesis (fat storage)
