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[9] [10] Classification [edit] Protein sequence and structure are important additional classification criteria for the three superfamilies (cytosolic, mitochondrial, and MAPEG) of GSTs: while classes from the cytosolic superfamily of GSTs possess more than 40% sequence homology, those from other classes may have less than 25%

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GPX4 engages directly with lipid hydroperoxides found in cellular membranes or lipoproteins (144,145)

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MOLPROBITY: Structure Validation and All-Atom Contact Analysis for Nucleic Acids and Their Complexes

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GPX4 serves multiple roles in its inhibition of iron-dependent ferroptosis regulated cell death 12,13,14

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