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61 Moreover, Notch signaling suppressed chondrocyte proliferation in the growth plate apparently independent of RBPjk while it also promoted both the onset and terminal progression of chondrocyte hypertrophy in a RBPjk dependent manner

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Indeed, the active form of vitamin D is generated not only in renal tubular cells but also in extrarenal target tissue cells, and its functions are autocrine, paracrine, and endocrine
