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facial edema (25%-50%), which is much less common than the edema caused by imatinib and mainly affects the periorbital region71

Future directions Several critical areas need further investigation to fully comprehend the complex relationship between the microbiome, TMAO, and cardiovascular disease

These lesions if diagnosed at an early in situ stage are potentially curable and definitely have a better prognosis, but unfortunately as they are clinically asymptomatic, it results in delayed diagnosis thus making the prognosis extremely poor