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Intervention Strategies: Anti-VEGF neutralizing antibodies (e.g., bevacizumab/B20) or anti-angiogenic tyrosine kinase inhibitors (e.g., axitinib), by blocking VEGF signaling, not only reduce pathological angiogenesis, edema, and hemorrhage but also decrease peripheral nerve density mediated by the interaction of VEGF with neuropilin (NRP), thereby alleviating pain

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B12 lipotropic supplements and injections have become increasingly popular tools for healthcare providers looking to support patient energy, weight management, and metabolic health
