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The increased hepatic exposure to insulin may also explain why obese subjects following exogenous GH administration respond better with higher increases of IGF-I than lean subjects

TCN2 is responsible for distributing B12 throughout the body, including the CNS

With a high cell-energy charge within hepatocytes, co-enzyme A (CoA) exists principally as acetyl-CoA which potently activates pyruvate carboxylase, directing pyruvate toward gluconeogenesis

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