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447,448,449,450 VGCCs, present in the presynaptic terminal, are responsible for neurotransmitter release and the propagation of pain signals to second-order neurons
Of further support, cultured astrocytes from postmortem tissue of patients with ALS are toxic to motor neurons [240]
However, it is essential to note that while exercise can have many beneficial effects, it is not a substitute for a healthy diet
