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Amponsah-Offeh M, Diaba-Nuhoho P, Speier S, Morawietz H

developed a pH-responsive charge-reversal polyelectrolyte, and an integrin V3 antibody-functionalized GO complex was developed for targeted, controlled release of DOX, enabling selective drug release in acidic intracellular organelles for enhanced cancer treatment [78]

Translational barriers and clinical limitations of CSC-targeted therapies A representative summary of clinical trials and approved CSC-targeting agents, including pathway inhibitors, immune therapies, and metabolic modulators, is provided in Table 1

This flexibility allows for use in a variety of laboratory tests and studies