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Others have identified astrocytes as a target for the neuroprotective effects of UA, demonstrating effects on astrocytic glutathione and Nrf2, and providing further support for the involvement of UA in antioxidative processes 52

The energy of GTP hydrolysis is used to pinch the mitochondrion into two smaller mitochondria

This spatial constraint enables precise signaling, exemplified by the NADPH oxidase 2 (NOX2) complex, which assembles at receptor sites in antigen-presenting cells (APCs) and phagocytes
