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Description
Domain I consists of a central four-stranded beta-sheet flanked on one side by two alpha-helices and on the other side by an irregular segment containing three short 3(10)-helices, while domain II is entirely helical
doi: 10.1038/s41598-020-74401-5
A mutant 2 AR in which all the phosphorylation sites are altered, such that there is no agonist-induced phosphorylation, shows impaired ubiquitination as well as significantly reduced -arrestin interaction [70, 80]
PMID: 12668216 Pavlova IV et al
