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2 The pooled data including 1,621 patients from ROCKET-1, -2, and -4 showed that IOP lowering with netarsudil 0.02% once daily (17.519.5 mm Hg) was comparable to that with timolol 0.5% twice daily (17.618.4 mm Hg) at nine time points through 3 months of treatment

This is especially relevant in the brain, where neurons have high metabolic demands and rely heavily on mitochondrial health

Evidence Quality Comparison# Side Effect and Safety Comparison# Dihexa Safety Considerations# The primary safety concern for Dihexa is specific to its mechanism

Though there appear to be no risk and few symptoms associated with too much B12, its wise to keep your level within the upper limit of the standard test range.