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These cytosine-phosphate-guanine (CpG) motifs are known to enhance transcriptional binding when not methylated, but in striking contrast, methylation of these sites is known to effectively silence gene transcription [21]

P.JonesM.et al (2010)
Sodium hydroxide is added to adjust pH (range 6.0 to 7.5)
Click-derived multifunctional metal complexes for diverse applications
