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While further studies are needed to assess longterm safety, dosing, and clinical relevance, the work points to a promising intranasal drugdelivery platform that emphasizes stability, retention, and neuroprotectionkey considerations for managing a chronic neurodegenerative disease

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Smith PD, Smythies LE, Mosteller-Barnum M et al (2001) Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS- and IgA-mediated activities

Thus, said treatment may be prophylactic (preventative), palliative, symptomatic and/or curative