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Among these genes, the expression of CP increased in astrocytes, the expression of HMGB1 increased in all types of cells, and the expression of TF decreased in oligodendrocytes (Table 2)
This network is only as strong as its weakest link
Watanabe, S., Kishimoto, T
Elucidation of the mechanistic basis of such synergistic effects could enable the design of rational combination regimens that use lower doses of cytotoxic drugs with fewer side effects and overcome multidrug resistance (Musso and Biscussi, 2025)
