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Esteras N, Dinkova-Kostova AT, Abramov AY (2016) Nrf2 activation in the treatment of neurodegenerative diseases: a focus on its role in mitochondrial bioenergetics and function
Nature 437 , 902905 (2005)
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Promising alternatives include intra-articular growth factors, metabolic modulators targeting oxidative stress, and autophagy inducers that restore mitochondrial balance