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Specifically, IL-1 is constitutively produced and retained in keratinocytes, but in response to several stimuli, IL-1 is released, which is essentially a primary event of inflammation

In these cases, treatment should be initiated as soon as possible.[] The etiology of vitamin B12 deficiency typically includes malabsorption-related causes such as autoimmune gastritis (pernicious anemia), celiac disease, inflammatory bowel disease, surgical gastrectomy, gastric bypass, and ileal resection

It also enhances skin elasticity and strengthens hair and nails

Some doctors are starting to listen: In one Swiss study (2), almost half of all general practitioners agreed with prescribing B12 for unexplained fatigue