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Conversely, elevated IL-22 expression promotes the aggregation of B cells and the formation of lymphoid aggregates, resulting in the upregulation of multiple cytokines including CXCL12 and CXCL13, ultimately leading to the production of autoantibodies (52)
Pastorino, J
Aquaporin-9 immunohistochemistry in varicocele testes as a consequence of hypoxia in the sperm production site
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