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doi:10.3390/cells9091970 (PMC7564605) Barton-Davis ER, Shoturma DI, Sweeney HL

In a prospective double-blind study of euthyroid subjects (6074 years old) receiving a seleniumyeast-based supplementation (100, 200, or 300 g Se/day for 5 years), decreases in serum TSH and fT4 concentrations but no changes in fT3 or the FT3/fT4 ratio were observed, indicating a dose-dependent effect on thyroid function even in healthy individuals [39]

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