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Establishing this foundational knowledge is the first and most critical step in ensuring that any development program for either entity is built upon accurate chemical data, a clear understanding of mechanistic action, and strict adherence to the specific compliance and safety protocols governing research substances
Levodopa monotherapy produced drowsiness in the first round of 131 PD patients and restricted the dosage of levodopa in 14% of patients (Lesser et al., 1979)
