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Glut9-mediated urate uptake is responsible for its protective effects on dopaminergic neurons in Parkinsons disease models
A higher risk of developing PD has been linked to variants in a number of PARK-designated (SNCA, UCHL1, LRRK2, PARK 16, GAK) and a few additional genes (MAPT, GBA, NAT2, INOS2A, GAK, HLA-DRA, and APOE) (Postuma et al., 2015)
IHH-4 and GLAG-66 cells were treated with 0, 1, 3.125, 6.25, 12.5, 25.0, 50.0 and 100 M of DB (cat no
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