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In a separate study of 5771 patients, those with increased serum B12 levels (above 455 pg/mL or 336 pmol/L) had increased all-cause mortality upon follow-up [123]

In comparison, GLP-1 induced a 22% decrease in body fat mass and a 4% reduction in lean mass

doi: 10.1016/j.biopsych.2013.10.010

As the Si-based agent was effective in treating UC in the brain and large intestine of mice, it was considered to be capable of suppressing exacerbations and sustaining remission of UC