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In addition, it is well known that high levels of NH 3 induced by high amino acid intake have toxic effects, especially for the brain and the kidneys (Reference Conway and Hutson69,Reference Davani-Davari, Karimzadeh and Sagheb72)

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10.1111/j.1365-2443.2008.01234.x Summary Keywords type 2 diabetes, GK rat tissues, exercise, ROS, mitochondria, energy metabolism Citation John A, Howarth FC and Raza H (2022) Exercise alleviates diabetic complications by inhibiting oxidative stress-mediated signaling cascade and mitochondrial metabolic stress in GK diabetic rat tissues