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The global sensitivity analysis suggests that the comproportionation reaction, R 5 , is not pivotal for the model OCR output, given that its parameters, k p5 and k m5 , are the two least sensitive parameters for both main and total interactions

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The cell cycle distribution also showed that knocking out MIA3 increased the number of cells in the G1/G0 phase and decreased the number of cells in the G2/M and S phases (Fig
