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Description
NAD + acts as a cofactor through its interplay with NADH, playing an essential role in many enzymatic reactions of energy metabolism, such as glycolysis, oxidative phosphorylation, fatty acid oxidation, and the TCA cycle
It binds to growthhormone secretagogue receptors (GHSR) in the hypothalamus and pituitary, reduces the inhibitory signal from somatostatin, and triggers a rapid GH pulse

doi:10.1038/cdd.2009.107, PMID: 19662025 Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging

In one small study, female athletes who consumed increased choline had greater weight loss, especially body fat, than those who did not
