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This contrasts sharply with corticosteroids and traditional immunosuppressants, which carry extensive lists of potential adverse effects
[DOI] [PubMed] [Google Scholar] Ha S.K., Smith A.P., Howden R., Dietrich W.M., Bugg S., O'Connell M.J., Goldsbrough P.B., Cobbett C.S
Reaction mechanism [edit] GPX4 catalyzes the following reaction: 2 glutathione + lipidhydroperoxide glutathione disulfide + lipidalcohol + H 2 O This reaction occurs at the selenocysteine within the catalytic center of GPX4
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