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[2] For BPC-157, a pentadecapeptide with no definitively identified receptor and a multimodal signaling profile involving the NO system, FAK-paxillin pathway, and VEGF-related angiogenic modulation, the toxicology assessment must rely more heavily on empirical observations from published preclinical studies than on mechanism-based predictions

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Most popular research peptides fail to meet these criteria and are often explicitly banned (Category 2)