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In their examination of the regulation of macrophages by CD38, Xu et al
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[4] [6] The direct delivery of ascorbic acid into the bloodstream allows for supraphysiological concentrations, which could have distinct biological effects, such as pro-oxidant activity in the presence of transition metals or selective cytotoxicity against certain malignant cells, although these applications remain under investigation and are not universally accepted as standard of care
hormonal confirmation), and confounding dietary or behavioral factors
