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In patients who are eligible for antiviral therapy, treatment should be initiated with one of the recommended first-line therapies (pegylated interferon-, entecavir, or tenofovir), and treatment efficacy should be monitored regularly for serum HBV DNA, alanine aminotransferase, and serologic responses

Practically, that means: Start extremely low sometimes at one-tenth or one-fifth of the usual initial dose

498,499 It regulates various cellular activities, including growth, cell death, and the ability of stem cells to reproduce themselves

Deglutathionylation of glutathionylated targets by GRXs is always associated with reactivation of target activity