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In mammals, cobalamin is a cofactor for only two enzymes, methionine synthase and L-methylmalonyl-coenzyme A mutase (2)

If you are displaying any of the signs and symptoms of B-12 deficiency, its best to contact your doctor immediately

This material is intended strictly for laboratory investigation and analytical use

The classic presentation of symptomatic B 12 deficiency occurs in Addison-Biermers disease, and is characterised by megaloblastic anaemia.9 This type of anaemia was the first condition to be linked to B 12 deficiency, and probably because of that, many doctors have the misconception that B 12 deficiency is ruled out in patients without anaemia