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The Brink: When you look at where this pandemic is goingwith the Delta variant, were hearing a lot more about breakthrough cases, indicating not that the vaccines arent effective, but that instead Delta is highly contagiousdo you think tweaks to vaccine formulations will be needed to protect against extremely infectious variants like Delta

& Liu, F

Additionally, accumulation of cyanocobalamin metabolites may occur in severe renal impairment, though this is rarely clinically significant

And honestly, they have a point