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Streubel R, Makara M, Guerrero TG

demonstrated that acute activation of PDH by DCA competed for pyruvate and partially reduced its flux through malic enzyme, which led to normalization of the myocardial triglyceride pool and improved contractile function

Sirtuin 3dependent mitochondrial dynamic improvements protect against acute kidney injury

doi: 10.1152/physrev.00062.2017 30 DingR.TanY.DuA.WenG.RenX.YaoH.et al