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Although the molecular role that reduced homocysteine plays in vascular disorders is unclear, experimental evidence indicates that the association between moderately elevated homocysteine levels and atherothrombotic disease is likely to be causal

For example, genes assigned to this function were the glutathione peroxidase 1 ( GPX1 , FC = 2.2) and 3 ( GPX3 , FC = 8.6) and the glutathione-S-transferase kappa 1 ( GSTK1 , FC = 26.9), omega 1 ( GSTO1 , FC = 15.1), omega 2 ( GSTO2 , FC = 9.9) and the microsomal glutathione-S-transferase 1 ( MGST1 , FC = 13.7)

Although the findings are preliminary there is evidence emerging from clinical trials to indicate that delta-9-THC and CBD (alone or in combination) can help alleviate various forms of pain, e.g., neuropathic pain, inflammatory pain, and pain associated with MS