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The H 2 O 2 is also capable of dissociating to form hydroperoxyl and hydroxyl radical: [2H 2 O 2 OH+ HOO+ H 2 O] (Koppenol and Hider, 2019)

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Reactive oxygen species (ROS) and proinflammatory cytokines caused by radiotherapy as well as cytotoxic agents are necessary for the physiological function of cells, but excessive production of these molecules damages cellular components such as proteins, lipids, and DNA (Park et al