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Notably, the clinical translation of MT remains faced with challenges, including the isolation of mitochondria, transplant rejection, bloodbrain barrier, and ethical issues [367369]

c-Myc has been demonstrated to play a crucial role in promoting the expression of genes associated with glycolysis, including Glut1, Glut2, Glut3, Glut4, hexokinase, phosphoglucose isomerase, phosphofructokinase, aldolase A, triose phosphate isomerase, glyceraldehyde-3-phosphate dehydrogenase, phosphoglycerate kinase 1, phosphoglycerate mutase, enolase, pyruvate kinase, and LDHA [141] (Fig

10.1080/08923973.2016.1274997 [DOI] [PubMed] [Google Scholar] Raine T., Bonovas S., Burisch J., Kucharzik T., Adamina M., Annese V., et al

Your body cannot make B-12 on its own, so it must come from diet or supplementation