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Description
Elevated SUA activates endothelial NF-B signaling, upregulating monocyte chemoattractant protein-1 (MCP-1) and intercellular adhesion molecule-1 (ICAM-1) expressions to accelerate atherosclerosis progression (Wang H

Substrate binding led to dimerization of SurA, where the substrate was located between the two P1 domains of the SurA dimer

Peptides are prescription medications

References 1 SmythePWilkinsonHN
