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However, it should be emphasized that the generalizability of our findings targeting PEX5, which undermines peroxisome biogenesis and integrity, may be limited in diseases with intact peroxisome biogenesis, including adrenoleukodystrophy, in which PEX5 expression and function are conserved and in which pathogenic mechanisms stem from disruptions in specific peroxisomal pathways rather than global peroxisome dysfunction

in those latter publications, morphine-induced receptor internalization was observed for longer time treatment compared to DAMGO

Whether the joint clinical decision-making will weaken the ability to get a COVID-19 vaccine is unclear, since it implies people should see a qualified health care provider before deciding on vaccination
