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Multiple sclerosis (MS) As a chronic inflammatory demyelinating disease of the nervous system, MS is characterized by the infiltration of T cells and B cells into the central nervous system, the excessive production of inflammatory cytokines and chemokines, and the failure of the immune system to present immune responses [47]
demonstrated a physical interaction between glutamine-induced MKP-1 and pcPLA2, suggesting that glutamine can directly deactivate cPLA2 via early induction of MKP-1 [81]
L., Langfelder P., Li X., et al
[DOI] [PMC free article] [PubMed] [Google Scholar] 170.Hicks S.D., Confair A
