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This is because vitamin B12 acts as a cofactor for neurotransmitters like serotonin and dopamine, both of which are key regulators of mood and emotion

In some cases, improvements in sleep and a reduction in behavioral challenges may occur

In support of such a mechanism, ovariectomy in female Keap1 iKO mice reduced the protein levels of both pGSK3 (i.e., inactive) and Nrf2 and effectively prevented MuSC loss (Fig

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