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Ackerman, S

By blocking NNMT, 5-amino-1MQ restores optimal NAD+ and SAM levels, improving cellular function before any external changes become visible

Further investigations of antioxidants and their role in influencing tissue regeneration via metabolic regulation are needed to determine whether reducing excess ROS in the stroma or stimulating the perturbation of cellular metabolism during wound healing may mitigate fibrotic processes to favor wound healing and scarless matrix deposition in KC

[DOI] [PubMed] [Google Scholar] [10].Ray PD, Huang BW, Tsuji Y, Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling, Cell