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As a result, pain is also highly associated with psychiatric comorbidities resulting in more severe pain, worse functioning and disability, lower quality-of-life, and higher incidences of opioid-use disorder [21]

When the body is in a pathological or physiological state, changes occur in the nature and quantity of metabolic products within cells

[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Laakso M., Fernandes Silva L

[249] [250] In October 2021, the EUA was expanded to include children aged 5 through 11 years of age
