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10.1038/ng1658 [DOI] [PMC free article] [PubMed] [Google Scholar] Ohgami RS, Campagna DR, McDonald A, & Fleming MD (2006)
Expression of Tim-3 drives phenotypic and functional changes in Treg cells in secondary lymphoid organs and the tumor microenvironment
Future research must integrate multi-omics data to develop individualized therapies, further investigate the stability and plasticity of polarization states, and leverage smart materials and advanced model systems to advance precision immunotherapeutics
Combined with potential increased fluid loss from GI effects, dehydration becomes a genuine risk
