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Thereby, BPC 157 is easily applicable and safe without adverse effects (i.e., in ulcerative colitis trials) while toxicology studies showed that a lethal dose (LD1) can be not achieved (for review, see [1,2,3,4,5,6,7,8,9,10])

10.1016/j.diabet.2016.03.008 [DOI] [PubMed] 52.Chapman LE, Darling AL, Brown JE (2015) The association between the biguanide drug metformin and vitamin B 12 deficiency in diabetic patients: a systematic review

If you plan to include this peptide in your routine, consulting a specialist is recommended

Darker skin may show persistent coloring changes with areas of both decreased and increased coloring
